Friday 25 November 2016

Malaria




In my last post I referred to a report from WHO and WMO, ATLAS OF HEALTH AND CLIMATE, where are mentioned a number of diseases that would be affected in one way or another by climate change, among them Malaria.

Malaria (probably meaning “bad air” as it was thought to be produces by air from marshy areas) is an illness caused by parasites transmitted to humans by specific mosquitoes. There are about 3,500 species of mosquitoes (grouped in 41 genera) (CDC) but it is the female of genus Anopheles which causes the main malarial problem. Malaria is mainly present in tropical and subtropical countries, infecting over 300 million people per year and causing the death of more than 1 million in the same period (MedLinePlus). By the way Anopheles means “useless, hurtful, harmful

This kind of transmission is denominated vector-borne disease (VBD), i.e. the infectious disease is transmitted to human from another human or from an animal through a living entity (WHO)




From now on I will introduce Notes in my blog, they are trying to aim you, the reader, to check about certain points that seems interesting to me but are not in line with the main course of this blog.




Note 1: if we consider the countries between the tropics we would have about 40% of the total world population and the same percentage of the world´s surface, it would mean that making some very basic numbers the portion of the people infected by malaria between the tropics would be approximately over 10% of the population of the region.
Recent research by Murdoch el al. shows that global warming could reduce the effect of malaria in some regions. They explain that some studies have shown the potential increase of the illness in cooler countries due to the increase in temperature. However, they show that this change, in the warm countries, would reduce the capacity of some of the vectors (the type mosquito carrying the parasite that produces the illness) to act as such and of the parasite itself due to distancing of the optimal temperature conditions. This is very interesting; in case this is proven to be realistic, it would mean that global warming would change the current health/diseases map of the world.

Note 2: Did you know that Europe is the first region in the world to be declared malaria free? WHO says so.
But let´s go back to malaria and climate change, other publications from a number of scientist from Europe and USA of 2015 (Perham et al.) expresses “While this is likely to take many forms (they refer to climate change), the implications for future transmission of vector-borne diseases (VBDs), given their ongoing contribution to global disease burden, are both extremely important and highly uncertain” i.e. the problem is so complex that so far any estimation is very uncertain, meaning they can take any path in the future. For me this is even more dangerous than having a clear consequence as in this last case it is clear what steps need to be followed to overcome the problem and the real possibility of accomplish these steps.  The article mentions a series of challenges/variables/aspects to consider when trying to understand the effect of climate change in VBDs (vector-borne diseases), among them:

1.       Socio-economic and socio-cultural aspects
2.       Selecting the appropriate way of measuring the illness
3.       Data availability
4.       Appropriate models
5.       Ecological aspects

So we have two investigations, one saying that global warming would reduce malaria in a part of the world and the other saying it is extremely hard to know the real effect.

Not being this confusing enough there is another study published in 2014 (Carminade et al.) in it the authors running a series of computational models found that changes in global temperature will favour the transmission of malaria in the tropics but they understand that there are other variables to take into account in future investigations.

If we go deeper in the methodology used by Murdoch et al., we can see they worked under laboratory condition isolating mosquitos from other external variables what makes very difficult to compare it with the other papers and maybe these results should be taking into consideration as a kind of feedback for a major model that includes the mosquito life dynamics.

At this stage I can say that for me the study by Parham et al. seems to express the status of the current climate change – illnesses affair. The problem, not only for malaria but for any vector-borne disease and probably for any other disease, is extremely complex with a great number of variables affecting it and with a high level of uncertainty, making very hard to get a real and quantitative evaluation of future consequences and associated problems.